Voltaren is recommended to non-steroidal (non-hormonal) drugs. May be antipyretic, anti-inflammatory and pain-relieving (drugs of diclofenac to enter the warehouse of the drug).
Remaining, sickly, the power of the faces is most pronounced. Later, yoga is widely used for the treatment of pain symptoms in case of ailments of the rukhovo system of the body, pain in the loins, infectious diseases, post-operative treatment.
The international name for the drug is diclofenac. Under the dієyu tsієї speech, Ide bіl, which not only helps the patient to become better, but allows me to proceed to the full exaltation. For example, people with an ailing back cannot be recognized for special jubilant gymnastics, the docks were only a little bit out of sight.
Release form
For injections, Voltaren is dispensed in ampoules, which can avenge diclofenac sodium with other additives. The carton box contains 5 ampoules of 3 ml of radin (75 mg) plus instructions for infusion. Motherland of prozor, maybe mothers of unscrupulous zhovtuvatiy vіdtinok.
stock
Diclofenac sodium enters the main warehouse of Voltaren. To lie before additional speeches:
- Metabisulfite.
- benzyl alcohol.
- Mannit. May sechogіnnі power and dopomogає vvoditi homeland z fabrics. Vіn vіlny vіd pіrogenu.
- Propylene glycol distillation.
- Sodium hydroxide for bringing the difference to the required acidity.
The antiseptic effect may be nonsteroidal speech diclofenac.
Indication
Zavdyaki antipyretic, anti-spasmodic, anti-painful diї, faces prescribe until zastosuvannya for the treatment of rich diseases. Just as soon as the drug was taken, only for the treatment of rheumatic diseases, the area of stoking the drug clearly expanded.
Voltaren injections are actively prescribed in rheumatology, surgery, gynecology, ophthalmology. Also stasis in the treatment of ENT diseases, infections, sports injuries.
This preparation of spreading zavdyaki spreads to the fact that the wine is easily tolerated by ailments, and victoriously overcomes the anti-painful and analgesic function. Effective in case of ailments.
Rheumatic illness
Zastosovuyutsya prick Voltaren, like a sick man:
- Degenerative disease of the musculoskeletal system.
- Osteoarthritis (, knee joint).
- See different. Specific - typhus, syphilis, gonorrhea, brucellosis and tuberculosis. Nonspecific - hematogenous spondylitis, ailment. Kümmel, Bekhterev.
- , arthrosis too thin.
Rejoicing with Voltaren during these ailments, it changes the ranking dullness, it decreases more and more during the hour of the drift of the snow, or else the stench peresbuvayut at the camp of peace. Through manit, scho to enter the warehouse of likiv and help to bring the motherland out of the body, to go off the swollen soft tissue, suglob.
Neurological illness
To relieve the pain-relieving effect, the drug Voltaren is prescribed for the relief of the ailing camp, which has a carpal tunnel syndrome.
Voltaren at viglyadі ukolіv zmozhe maximally dopomogt ailing with migraine. In other cases, the drug is mostly powerless.
With ailments of ENT organs
At the warehouse of complex therapy, Voltaren injections can be congested with various ENT infections: tonsillitis, pharyngitis, otitis media.
Gynecological illness
Doctors can write in these cases, as if a woman is afraid of dysmenorrhea - it is very painful at the hour of menstruation. Diclofenac is not only less painful, but it can also reduce the amount of vision, a change in severe blood loss. For the first symptoms of dysmenorrhea, prescribe injections of 50 to 150 mg of Voltaren. If you don’t miss it, then continue the course until a few days.
It zastosovuyut, as if ignited the ignition process in the small pelvic cavity, as well as when the uterine appendages are inflamed - adnexitis. After carrying out various operations in the field of state organs, injections are prescribed to prevent adhesions.
Oncology
The rest of the research showed that diclofenac takes part in the development of cancer cells. Until then, the injections will change the pain in oncology.
Contraindication
In the packaging of an absolutely skin medicinal product, there is an instruction from the zastosuvannya, in which the warehouse of drugs is indicated, showing that contraindication.
For example, Voltaren is a contraindication for ailments of the schlub, but if someone does not understand, like an injection in case of pain in the back, it can be injected into a new one. On the right, diclofenac, which enters the warehouse of Voltaren, is a non-selective drug, which literally pours into the skin cells of the body. To this very reason, this drug can be a silent contraindication, but sometimes it can not cause anything with the main ailments.
Contraindication before congestion:
- Individual intolerance to diclofenac and other similar drugs.
- "Aspirin" bronchial asthma.
- Virazka sluice and 12-colon intestine, gastritis, duodenitis. Therefore, diclofenac reduces the function of the mucous membrane of the slough. Later, hydrochloric acid starts to ruin the walls of the duct and leads to various duct-intestinal ailments.
- With vagity, Voltaren is rarely prescribed. Yakscho zastosuvannya the drug is still necessary, then the drug should be prescribed as tablets, gel or powder. The effectiveness of diclofenac, which is administered in tablets/powder, will decrease due to the amount of blood juice and blood, and, later, having poured into the future matir will be insignificant. In the third trimester, faces are not assigned - this kind of glee can destroy the health of the uterus.
- In the period of breastfeeding (lactation period), the next drug should be replaced.
- Ill nirok. Oskilki drug may sechoginnі authority.
- Early child age. Even though it is still necessary to stop, then the dosage of the drug can be attributed to the rozrahunka on the baby’s head. For children under 6 years of age, it is recommended to use other, more sparing preparations, which should not contain diclofenac.
Only the doctor makes a decision about the recognition of the drug, the validity of its application.
Pobichna diya
These side effects are typical for all non-hormonal drugs. Some ailments can enjoy them for a long time of rich fates, others become nasty after the first course of healing.
The skin preparation is guilty of being a lesser drug. Before that, at the skin packaging there is an instruction, so it is necessary to respectfully read, after which you can proceed to the likuvannya.
Vіd Voltarena may suffer damage to the organs of the herbal system. Such behavior was feared to occur in people who had not previously suffered from problems with the intestinal tract.
Maybe nudota will appear with vomit, carry it, otherwise, navpaki, constipate. Sometimes they are afraid of bleeding and erosion, having broken through the folds and the swelling will become the 12-colon intestine.
The greatest risk of damage to the mucosal-intestinal tract is in such situations:
- Shkіdlivі zvichki: priyom alcohol, kurinnya.
- Virazkov's ailment of the slough and 12-colon intestine in anamnesis.
- The presence of the bacterium Helicobacter pylori.
- Vzhivannya їzhi, zdatnu significantly increase the secretion of mucosal-intestinal juice: gostra, fat, smoked, super-salty їzha. People suffer the same way, like to love chips, gassed on a drunken basis.
- One-hour administration of 2 or more non-steroidal anti-inflammatory drugs.
- Vik, scho cross the threshold of 65 years.
- Taking glucocorticoids at the same time from the NPSH.
- The results show that women are more scalable to negative impact on the group of drugs.
Also registered in the development of hepatic insufficiency.
From the side of the central nervous system, weakness, confusion, turbidity, bіl head, sleeplessness, malice or navpak, drativity are observed. Sometimes there is a decrease in the dawn, nervous tics.
Allergic reaction vinikaє dosit often. It is hanging on the shkіrі and sverbіzh, kropiv'yanka, especially in the area of introduction of lykіv.
We thought to ourselves unimportantly, turned to the doctor for help. You can’t get information from someone else about those who are bad for you after the introduction of likings - so you can improve your health more strongly.
Intra-language languages
Rozchin Voltaren of appointments for both internal and external stosuvannya.
Rozchin to be introduced internally in the language of the middle. Voltaren pricks need to be administered to dry the skin and the skin at the upper part of the middle ground. In another fall, you can drink your bare head into the side canal, which means paralysis of the leg. Inject the ampoules by pulling dobi 1 time. Sometimes, in extreme situations, the doctor prescribes infusions 2 ten days a day with an interval of sprat (alternatively three times) years. The offensive injection is necessary to work in another day. It is better to cherguvat the seats for skin injections.
Also, injections of Voltaren can be taken with other types of these drugs. Tse mozhut buti needles, candles, powder too.
It is important to understand that diclofenac is the main drug of injections of Voltaren, as it is also used in candles, tablets, powder. Therefore, in order not to exceed the permissible additional dose of diclofenac, it is not only the amount of diclofenac in ampoules, but also the concentration in tablets, powder, etc. that is to be avoided.
The main function of these faces is to take away the bill, to make it more normal, to fully exult. For example, carry out with rheumatic diseases.
Varto signify that the injections of Voltaren most often hit the cob stage of the disease. After passing the course of injections, the sick person should be transferred to sparing non-steroidal patients.
Internal drippers
Before this, put a urticaria with Voltaren, dilute it with 100 ml of dextrosy 5% or physical. Trivality of urticaria installs a medicine, fallow in case of overrun of ailment, pain syndrome.
The trivality of the urticaria is restored to the ailing. Tse mozhe buti 30 hvilin or 3 years. If there is a strong attack of pain during the postoperative period, then 25–50 ml of Voltaren is administered intravenously for 15–60 minutes. Give the speed of administration of the drug to be reduced.
Patients, yakі robili іn'єktsії Voltaren, it seems that the pain seems to pass approximately through the first half of the year. Just as soon as I take Voltaren in tablets, suppositories or powder, an analgesic effect can be reached in just a year or so. Have a good mood for a long time for 6 (maximum 8) years. I’ll lie down with a mustache, I’ll be healthy, sick, sick.
Interaction
In the case of Voltaren, if you take diuretics for ailments, it beckons to enter the warehouse, because there is a strong sechoginny effect.
In case of one-hour stagnation of Voltaren with other types of diuretics, the body may be more strongly hydrated. And it was a waste of money to bring potassium before the end.
Voltaren should not be taken with other non-steroidal anti-inflammatory drugs. The effectiveness of this does not increase, but then the side effects of an allergic reaction may appear in the sub-military force.
Stop Voltaren to promote blood pharyngeal and change it. Also, yoga cannot be done at the same time as anticoagulants. So do not follow Voltaren with aspirin - it neutralizes diclofenac, and paracetamol - there is a harmful injection on the liver.
Trivality to the course of likuvannya, as well as the dosing of the drug. At the same time, you can’t engage in self-deception, take additional painkillers - you can only hurt yourself more.
Even though the pain is stronger, or Voltarena pripinyaetsya - savage to fahivtsya. Possibly, I will add the drug, otherwise I will change it.
Drug therapy for osteochondrosis may be dependent on the use of various drugs. Pershochergov's task of the doctor to help patients with pain syndrome and burn out. For whom the neurologist prescribes non-steroidal anti-inflammatory drugs, shortened NPZZ. Tsі lіkarskі zasobi bathe bіl and vplyvayut on the fire of the fire.
One of such preparations, Voltaren, is used in tablets, gel, rectal suppositories, injectables and injections.
The drug looks like a gel
Voltaren gel prescriptions for healthy constipation. The main agent of the drug, diclofenac, can lie up to the NPZZ group, it causes inflammation and inflammation. In case of osteochondrosis of the cervical spine (as well as other localizations of diseases), doctors prescribe Voltaren gel until it is stopped. The cream of the main divinity, vin znimaє m'azovі spasms, change the swelling, turn the fragility of the affected segment.
The advantage of the drug is that the gel is allowed to be administered to children for 12 years. Voltaren apply the gel without interruption to the wounds with an ailment, gently rubbing into the skin. Dali, to recommend to dress up the cut-out case with gauze cloth. In case of osteochondrosis of the cervical ligament, the dressing is more likely to not work - to apply a folded bandage of gauze and close it behind an additional adhesive plaster. In some cases of side effects (sverbezh, whiskers), the bandage is known - in some cases, the drug is not adnexal to zastosuvannya. Also, do not apply zasib on festering or bleeding wounds.
The drug looks like an injection
The release form of the drug is ce ampoules with a design for intravenous injection. Inject Voltaren to stop at the acute stage of osteochondrosis of the cervical and other vertebral ridges. A short term used for injections is the use of pain syndrome and inflammation. Follow the course for 2 to 3 days (which is sufficient for the adoption of an acute pain syndrome), after which the injection should be advised, prescribing Voltaren tablets before taking.
To put injections once a day, vicorist, one ampoule of medicinal rozsin, it starts after 1.5 years, and the effect is trimmed by stretching the doby. Introduce the next inner language (yagidka or the upper part of the quilt). Inject Voltaren together with other drugs. The additional norm of the medicinal product does not exceed 150 mg.
Recognize Voltaren at Vighidi IN'єktziya Roschin guilty of the rejection of the Ushvanni Yolivikh, the victory of the Estrates is wounded-can be the viniknuti of the rosladi of the Shlunk-Chishka tract, manifest themselves of the cersesenni-senni, migrants, depressed dungeon, marshmallows, marshmallows.
Tablets and suppositories
Voltaren tablets are prescribed more importantly after the use of an acute phase of illness. Dosage of a rozrakhovu likar, depending on the individual indications of the patient. The tablet form of the drug is late, after 4 years, the protein does not affect the effectiveness. The drug is administered by a natural route from the cut and feces.
There are two types of pіgulok - first, in obolontsі and others, with stepwise fluctuations in fluffy speech (Voltaren retard). For the first time, I usually take 1 tablet trichi per day. For children up to 16 years of age, tablets are prescribed exclusively in obolontsi. It is within the competence of the doctor to continue the course of treatment, if possible, take 1 tablet of the drug 2 times a day.
Voltaren retard take 1 tablet a day, more importantly at bedtime, for children this kind of contraindications. The additional norm for the drug in case of osteochondrosis of the cervical spine, as well as other forms of ailments, is 150 mg.
Rectal suppositories are prescribed exclusively for adults. The norm of speech with primary intake of 100 mg. Dali, after dosing to become 150 mg, as divided into two doses (early and evening). Like a candle, they prescribed you as a supplementary prescription, and the head drug is a tablet, the medicine gives a read instruction on how to dose (maybe, taking the pills will be short).
Plastiir zastosuvanya
Like other pharmacological forms of the drug, Voltaren Plaster can be used against diclofenac (smut smut rechovina). In case of any need to lie down in the rozmіru viroba - plaster 70x100 mm 15 mg, and 100x140 mm 30 mg Diclofenac. The cream of the main fluffy speech, the plaster to replace the additional components that protect the skin of the afflicted vіddіl vіd poshkodzhen, aromatize virib.
Plastir of appointments for the missive infusion. Indication before zastosuvannya - osteochondrosis, be it localization. First, put a vibrib on the ailment of the village, from the new one, they will kill the spitting.
Plasters can be pain-free, anti-abrasive and anti-abryakov, and the effect is saved by stretching the doby. The course of treatment is three 2 days, but if necessary, the next day the therapy with the doctor will be continued for 1 day.
Contraindications - ce dermatological problems, fluctuations in the integrity of the skin curves and individual intolerance to drugs in the NPZZ group. The period of pregnancy and breast vigoduvannya, child age (up to 15 years of age) is also considered until contraindication. Tsya stattya mestit lest zagalni vіdomosti about the drug Voltaren and not є іnstruktsієyu until zastosuvannya. First, take the doctor's advice, obov'yazkovo consult a doctor.
Before the warehouse of injections of Voltaren, so that you can read the instructions from the zastosuvannya, already know our readers and descriptions on our portal of diclofenac sodium. The presence in Voltaren's injections of speech indicates antipyretic, analgesic and antispasmodic for this pharmaceutical preparation. Transferred power to the drug can be suffocated by it prostaglandins, especially speech in the body of a person, indicative of inflammation and temperature rise.
Instructions for administering Voltaren injections
Instructions for administering Voltaren's injections describe them as an indispensable speech in the treatment of rheumatic lesions of the loam and soft tissues. Injection of Voltaren in injections allows a positive injection on the musculoskeletal system, reduces swelling of the joints and relieves pain symptoms.
Indication before zastosuvannya
Instructions for injecting Voltaren injections report on indications before injecting the drug:
- inflammation and degenerative lesions of the musculoskeletal system (osteoarthritis, rheumatoid arthritis, ankylosing spondylitis);
- sickness of the ridge;
- fuses infecting soft tissues with a rheumatic character;
- gout (in the treatment of acute attacks);
- adnexitis and primary dysmenorrhea;
- zhovchnі and nirkovі kolki;
- migraine;
- Infectious lesions of the ENT organs in otitis, pharyngitis and tonsillitis.
Price for injections of Voltaren
As a rule, Voltaren's formulations for domestic injections are produced by the Slovenian "Naklofen". In ampoules of 3 ml, 75 mg of active speech is contained. Also, on the Russian market it is possible to introduce such a drug, which is produced by the Swiss pharmaceutical concern Novartis.
If you value Voltaren's injection, then it is fully available. So a package of 5 ampoules in an average cost of 260 to 290 rubles. Tsі tsіni є orientovnimi, oskolki їх kolivany rich in what zalezhatimut vіd vіdnya trading nasіnki that region of our country.
How, where and how do you inject Voltaren?
As for the methods of injecting Voltaren injections, the stench vibrates internally. Imovirnist development of side effects and multiple contraindications before Voltaren's injections were zoomed in on yoga in short courses.
Practice has shown that for more than two days it is not possible to stop the injection of Voltaren. Nadalі їх sіd replace zastosuvannym tabletovanі drug form or suppositories. Іn'єktsiї cytogo drug robylyatsya no more often than 1 time for production. In important, zanedbanih depressions with high intensity of inflammation and pain symptoms, a dose of 75 mg of active speech is allowed for doba. Zdіysnyuyut such an introduction with a pause for a couple of years. You can combine injections with other forms of the drug, but remember that the additional dose of Voltaren is not guilty of overdosing 150 mg.
Contraindication for zastosuvannya.
If you talk about contraindications before the injection of Voltaren, then the instructions for how to stop it should be noted that yoga cannot be given to patients with:
- virazkovy lesions of the intestinal tract;
- bronchial asthma;
- kropivyankoy;
- allergic reactions to non-steroidal hormonal drugs;
- did not reach the age of 18;
- women in the third trimester of pregnancy;
- hostile rhinitis and polyposis of the mucous membrane of the nose.
Important! This material is a popularized version of the classic instructions for the injection of Voltaren injections. Vin does not claim to be encyclopedic accuracy and therefore cannot be an instruction for self-administration of the drug. Do not engage in self-deception. A great list of possible side effects due to the use of this drug is indicated only after consultation with the doctor. Only fahivets can call all “pros and cons” in the nutritional docile recognition of Voltaren’s injections.
Possible side effects
Nebezpeka development of side effects, many of which are not safe for the health and life of the patient, have been brought to the point that you cannot get the drug without a doctor's prescription.
Below is a list of side effects of Voltaren injections, depending on the instructions for injecting the drug:
- Increased sensitivity to the storage drug, which manifests itself in bronchospasm, vasculitis, arterial hypotension, pneumonia;
- Pain in the epigastrium, vomit and nausea, worse gas production, abdominal cramps, intestinal or ductal bleeding;
- Anemia, agranulocytosis, thrombocytopenia;
- Miscellaneous reactions in the areas of administration of the drug, which are manifested in the appearance of necrosis, abscesses;
- Pain behind the sternum; promotion of arterial pressure; increased heart rate;
- Headaches and drowsiness, confusion, judgment, disorder of memory, loss of orientation, depressive and drative reactions;
- Nephrotic syndrome, swelling, nirkov deficiency.
Side effects from the side of the neurological system in looking at the patient's orientation or drowsiness are the fault of the patient's symptoms, connected with car care, or robots with tools and possessions that require the use of psychomotor reactions.
fluffy speech
Release form, warehouse and packaging
Rozchin for internal language introduction bezbarvny chi light yellow.
Additional speech: (Vilniy vіd pirogenіv) - 18 mg, propylene glycol distillation - 600 mg, benzyl alcohol - 120 mg, sodium bisulfite - 2 mg, sodium hydroxide d/i - up to pH 7.8-8.0, water d/i - up to 3 ml .
3 ml - glass ampoules with a broken point or a ring of evil (5) - packs of cardboard.
Pharmacological activity
To avenge diclofenac sodium, the speech of non-steroidal structure, which can be shown to be antiseptic, analgesic and antipyretic. The main mechanism of diclofenac diclofenac, put into the minds of the experiment, is the galvanization of prostaglandin biosynthesis. Prostaglandini play an important role in the pathogenesis of inflammation, pain and fever.
In vitro, diclofenac sodium, at concentrations equivalent to thym, which can be reached when treated by the patient, does not affect the biosynthesis of proteoglycans in cartilage tissue.
In case of rheumatic diseases, the anti-inflammatory and analgesic powers of Voltaren provide a clinical effect, which is characterized by a significant change in the manifestations of such manifestations of disease, such as calmness in Russia, mild stupor and swelling of the joints, as well as improvement of the functional state.
An analgesic effect of the Voltaren preparation was noted for mild and severe pain of non-rheumatic walking. Pain relief occurs after 15-30 whilins. In case of post-traumatic and post-surgery flare-ups, Voltaren quickly relieves pain, changes the fuse and post-surgery wounds. In vicarious combinations with opioids in patients with postoperative pain, Voltaren significantly reduces the need for opioids. In addition, Voltaren relieved migraine attacks.
Pharmacokinetics
Vsmoktuvannya
After intravenous (i.m.) administration of 75 mg of diclofenac, smokying begins negligently. C max average value becomes close to 2.5 µg/ml (8 µmol/l), reachable after about 20 minutes. The number of active speech, which is wetted, is in linearity depending on the size of the dose of the drug.
The area under the "concentration-hour" (AUC) curve after intravenous administration of Voltaren is approximately 2 times greater, lower after oral or rectal ingestion, and in the remaining drops, about half of the amount of diclofenac passes through the liver.
With a low introduction of the drug, pharmacokinetic indications do not change. For the duration of the intervals that are recommended, there is no cumulative effect between the administration of the drug.
Rozpodil
Connection with blood serum proteins - 99.7%, more importantly s (99.4%). It is possible to reach a limit of 0.12-0.17 l/kg.
Diclofenac penetrates into the synovial cavity, and the maximum concentration is reached at 2-4 years of age, lower in the blood. The period of napivvedennya from the synovial cavity is set to become 3-6 years. After 2 years after reaching the maximum concentration in plasma, the concentration of diclofenac in the synovial cavity, lower in plasma, and її values are overlaid with a greater stretch for a period of up to 12 years.
Diclofenac has been reported at low concentrations (100 ng/ml) in the breast milk of one year old mothers. The amount of the drug, which is consumed through breast milk in the body of a child, is transferred, equivalent to 0.03 mg / kg / day.
Metabolism
The metabolism of diclofenac is often affected by the glucuronidation of an unchangeable molecule, but, more importantly, with the help of a one-time bagatorase hydroxide treatment and methoxyl treatment, which leads to the adoption of decal phenol metabolites (3 "-hydrox-, 4"-x-droxy , 5-dihydrooxy- and 3"-hydroxy-4"-methoxydiclofenac), most of them are converted to glucuronide conjugates. The bottom of the phenol metabolite is biologically active, and less importantly, diclofenac.
Vivedennya
The global systemic plasma clearance of diclofenac becomes 263±56 ml/min. Kіntsevy period napіvvivennya become 1-2 years. T 1/2 of 4 metabolites, including two pharmacologically active ones, is so nontrivial and becomes 1-3 years. One of the metabolites, 3"-hydroxy-4"-methoxy-diclofenac, may have a longer drank period, the protein metabolite is mostly inactive.
Approximately 60% of the dose of the drug is administered through the cross section of both glucuronic conjugates of the unaltered active speech, and also of metabolites, most of which are also glucuronic conjugates. An invariant appears to have less than 1% diclofenac. Part of the dose of the drug, which is left out, is excreted in apparently metabolites from the liver.
The concentration of diclofenac in plasma linearly depends on the magnitude of the dose taken.
Pharmacokinetics in a wide range of ailments
After smoking, metabolism and excretion, the drug should not be left in vіku. However, in some patients of the frail age, a 15-minute intravenous infusion of diclofenac resulted in an increase in the plasma concentration of the drug by 50%, compared with that in older patients.
In patients with impaired function of the nirok cumulation of unaltered active speech is not observed under the recommended dosing regimen. When CC is less than 10 ml / min, the rozrachunkovsky equal concentration of diclofenac hydroximstabolites is approximately 4 times higher, lower in healthy volunteers, with which the metabolite is excreted exclusively from the liver.
In patients with chronic hepatitis or compensated liver cirrhosis. indications of the pharmacokinetics of diclofenac are similar in patients without liver disease.
Indication
- inflammation and degenerative disease of the musculoskeletal system: rheumatoid arthritis, ankylosing spondylitis and other spondyloarthropathies; osteoarthritis; gouty arthritis; bursitis, tendovaginitis;
- Illness of the ridge, which is accompanied by pain syndrome (lumbago, ishialgia, ossalgia, neuralgia, myalgia, arthralgia, sciatica);
- nirkova and colic;
post-traumatic and postoperative pain syndromes that accompany inflammation (for example, in dentistry and orthopedics);
- Severe attacks of migraine.
Contraindication
- Virazka of the intestine chi;
- increased susceptibility to diclofenac and any other ingredients of the drug, including sodium metabisulfite;
- Voltaren contraindications to these patients, in some cases of attacks of bronchial asthma, kropivyanka or hostile rhinitis, are provoked by other NPZZs, as well as by any drugs that suppress the production of prostaglandins;
- Voltaren for injections is not prescribed for children and young adults under 18 years of age;
- Voltaren is not recommended for injections during pregnancy.
For protection
При застосуванні препарату Вольтарен та інших НПЗЗ необхідно ретельне медичне спостереження за хворими, які мають виразкове ураження шлунка або кишечника, інфекцію Helicobacter pylori, виразковий коліт, хворобу Крона, порушення функції печінки в анамнезі або хворими, які пред'являють скарги, що вказують на захворювання SHKT. Risk of development of slunic-intestinal bleeding with increased doses of NPZZ or due to the presence of a history of a viral infection, especially bleeding and perforation of a viral infection in older patients. Special precautions should be taken when taking Voltaren drug in patients, if you want to take drugs that reduce the risk of mucosal-intestinal bleeding: systemic glucocorticosteroids (including prednisolone), anticoagulants (including warfarin), antiaggregants (including including clopidogrel), acetylsalicylic acid) or selective serotonin serum inhibitors (including citalopram, fluoxetine, paroxetine, sertraline).
Precaution is necessary when Voltarsn is prescribed in patients with lungs and moderately impaired liver function, as well as in patients with hepatic porphyria, because. The drug can provoke attacks of porphyria.
Слід з обережністю застосовувати препарат у пацієнтів з бронхіальною астмою, сезонними алергічним ринітом, набряком слизової оболонки носової порожнини (в т.ч. з носовими поліпами), ХОЗЛ, хронічними інфекційними захворюваннями дихальних шляхів (особливо асоційовані з алергічними захворюваннями).
Особлива обережність потрібна при лікуванні пацієнтів із серцево-судинними захворюваннями (включаючи ІХС, цереброваскулярні захворювання, компенсовану серцеву недостатність, захворювання периферичних судин), порушеннями функції нирок, включаючи хронічну ниркову недостатність (КК 30-60 мл/мнн), діелнпідемією діабетом, гіпертонічною хворобою , under the likovanni ailments of the patsіtіntiv ailments, they are angry with alcohol, with the likovanni lіtnikhihi, the yaki is abdicated by the abstract of the pepper, and the ili is the meaning of after massive surgical interventions.
Carefully administer the drug Voltarev in patients with defects in the hemostasis system. Be careful when taking Voltiren in patients with a risk of developing cardiovascular thrombosis (including myocardial infarction and strokes). Be careful when taking Voltaren in patients with a frail age. This is especially relevant for the weakened, or may have a low weight of the body of people of a frail age; They are recommended to prescribe the drug at the lowest effective dose.
Special precautions should be taken with the intravenous administration of the Voltaren preparation. We are ill with bronchial asthma through the risk of acute illness, because sodium bisulfite, what to avenge in preparations, building disease and severe hypersensitivity reaction.
Dosing
Voltaren, rozchin for intravenous injections, followed individually, with the method of reducing the risk of developing side effects
Effectively, it is recommended to use the minimum effective dose, as little as possible, with the shortest possible period of treatment, apparently with the method of treatment and the camp of the patient.
Voltaren in ampoules is especially suitable for cob exacerbation of inflammation and degenerative rheumatic diseases, as well as pain after inflammation of non-rheumatic inflammation.
Voltaren should be administered by way of deep injection into the middle ground. Do not stop injecting Voltaren more than 2 days later. If necessary, treatment can be continued with Voltaren in tablets or rectal suppositories.
When conducting internal injections, in order to get rid of nerve damage or other tissues, it is recommended to follow the advancing rules.
The drug should be injected deeply internally at the upper outer quadrant of the lateral region. The dose should be 75 mg (in 1 ampoule) 1 time per doba. In important cases (for example, with colic) like vines, they can be carried out 2 injections of 75 mg each, with an interval at a sprat of years (another injection is due to be carried out in the adjacent region). As an alternative, one injection of the drug per day (75 mg) can be combined with other dosage forms of the drug Voltaren (tablets, rectal suppositories), in which case the total additional dose is not guilty of overdosing 150 mg. With migraine attacks, the best result is achieved, as Voltaren should be administered earlier after the onset of the attack, internally at a dose of 75 mg (1 amp.), With a further intake of suppositories at a dose of up to 100 mg the same day, as needed. The total additional dose is not guilty of overdosing 175 mg the first day.
Rozchin the drug can be clear. Not a trace of victorious rozchin from crystal or other siege. The ampoule of the drug should be vikorated only once. Rozchin is guilty of buti introductions negaly after the ampoule rosette. After a one-time injection of a non-corrosive drug for the treatment of an excess of the drug Voltaren, it is no longer necessary to stop. Do not change the name of the drug Voltaren, which is administered in ampoules, with other medical procedures for injections.
Children and teenagers up to 18 years old
Voltaren is intended for injections, does not slud zastosovuvaty in children and up to 18 years of age in connection with the difficulties of dosing the drug; if treatment is necessary in this category of patients, Voltaren can be administered in tablets or suppositories.
Summer patients (> 65 years)
Patients with disease of the cardiovascular system or high risk of disease of the cardiovascular system
It should be especially careful to administer the drug in patients with diseases of the cardiovascular system (including those with uncontrolled arterial hypertension), or in high risk cases of disease of the cardiovascular system. If trivalotherapy is necessary (more than 4 cycles) in such patients, the drug should be stopped at an additional dose, but not exceeding 100 mg.
Patients with impaired lung function and moderate severity
There is no data on the need for dose adjustment in case of drug ingestion in patients with impaired lung function and moderate severity through the next day of safety of drug ingestion in this category of patients.
Patients with impaired lung and moderate liver function.
There is no data on the need for dose adjustment in case of drug ingestion in patients with impaired liver function of the lung and the middle degree of severity through the daily follow-up of the safe ingestion of the drug in this category of patients.
Pobichna diya
The lower cases were brought to the unfortunate appearances, as they were revealed at the first hour of clinical cases, as well as when diclofenac was stagnant in clinical practice.
To assess the frequency of non-emergency events, the following criteria were used: very often (> 1/10), often (> 1/100,<1/10) нечасто (>1/1000, <1/100), редко (>1/10 000, <1/1000), очень редко (<1/10 000), Для каждой системы органов нежелательные явления сгруппированы в порядке убывания частоты их встречаемости. В пределах каждой группы, выделенной по частоте встречаемости, нежелательные явления распределены в порядке уменьшения их важности.
From the side of the blood and lymphatic system: more rarely - thrombocytopenia, leukopenia, hemolytic anemia, aplastic anemia, agranulocytosis.
From the side of the immune system: rarely - hypersensitivity, anaphylactic / anaphylactic reactions, including decreased arterial pressure and shock; even more rarely - angioedema (including an individual).
Psychic damage: even more rarely - disorientation, depression, sleeplessness, nightmarish dreams, dramatization, mental breakdown.
From the side of the nervous system: often - headache, confusion; rarely - drowsiness; even more rarely - impaired sensitivity, including paresthesia, memory disorder, tremor, seizures, apparent anxiety, acute disorders of cerebral circulation, aseptic meningitis.
From the side of the organ zor: more rarely - damage to the dawn (clouded dawn), diplopia.
From the side of the organ of hearing that labyrinth damage: often - vertigo; even rare - hearing impaired, noise at the wahah.
From the side of the heart: infrequently - myocardial infarction, heart failure, apparent heartbeat, chest pain.
From the side of the vessel: more rarely - elevated AT, vasculitis.
From the side of the dichal system, the organs of the thoracic cell of the mediastinum: rarely - bronchial asthma (including back); rarely - pneumonitis.
From the side of the shlunkovo-intestinal tract: often - abdominal pain, nausea, vomiting, diarrhea, dyspepsia, flatulence, decreased appetite; rarely - gastritis, duct-intestinal bleeding, blood vomitting, melena, diarrhea with blood clots, dimples of the intestinal duct (or without bleeding and perforation); more rarely - stomatitis, glossitis, stomatitis, phrenic strictures in the intestines, colitis (nonspecific hemorrhagic colitis, acute viral colitis or Crohn's disease), constipation, pancreatitis, dysgeusia.
From the side of the liver and the living paths: often increased activity of aminotransferases in blood plasma; rarely - hepatitis, zhovtyanitsya; impaired function of the liver; more rarely - bliskavichny hepatitis, liver necrosis, liver failure.
On the side of the number and sub-shkirnih fabrics: often - shkirny visip; rіdko - kropiv'yanka; more rarely - bullous dermatitis, eczema, erythema, bagatoform erythema, Stevens-Johnson syndrome, Lyell's syndrome (toxic epidermal necrolysis), exfoliative dermatitis, sverbіzh, alopecia, photosensitivity reactions; purpura, Henoch-Schonlein purpura.
From the side of nirok and sichway paths: even more rarely - gastric insufficiency, hematuria, proteinuria, tubulo-interstitial nephritis, nephrotic syndrome, papillary necrosis.
Zagalni discord and damage at the mist of the introduction: often - bіl, oshchіlnennya at mіstsі іn'єktsії; Rarely - swelling, necrosis at the injection site.
These clinical reports indicate a small increase in the risk of cardiovascular thrombotic complications (for example, myocardial infarction), especially in case of a severe congestion of diclofenac at high doses (an additional dose of 150 mg).
Even if the side effects are indicated in the instructions, they will help, or you remembered if there were other side effects that were not listed in the instructions, please tell us about the purpose of the doctor.
Overdose
Symptoms: vomit, slough-intestinal bleeding, diarrhoea, constipation, wheezing noise, sudomi. In times of significant impairment, there is a possible development of acute nirk insufficiency and damage to the liver.
Likuvannya: symptomatic relief is indicated for such complications as decreased arterial pressure, nirk insufficiency, convulsions, damage to the side of the mucosal-intestinal tract, and dementia. Forced diuresis, hemodialysis or hemoperfusion are not effective for dnclofenac, because active speeches and preparations in a significant world
bind with plasma proteins and are subject to intensive metabolism.
Medical interaction
Shown in mutual modality
Potency inhibitors of CYP2C9. In case of total recognition of diclofenac and pancreatic CYP2C9 inhibitors (such as voriconazole), it should be protected through the possibility of an increase in the concentration of diclofenac in the blood serum and an increase in systemic disease caused by the metabolism of diclofenac.
Lithium, digoxip. Diclofenac may increase the concentration of lithium and digoxin in plasma curves. It is recommended to monitor the concentration of lithium, digoxin in blood serum.
Diuretic and hypotensive diseases. With one-hour congestion with diuretics and antihypertensive drugs (for example, beta-blockers, ACE inhibitors), diclofenac may reduce the hypotensive effect. Тому у пацієнтів, особливо літнього віку, при одночасному призначенні диклофенаку та діуретиків або гіпотензивних засобів слід регулярно вимірювати артеріальний тиск, контролювати функцію нирок та ступінь гідратації (особливо при комбінації з діуретиками та інгібіторами АПФ внаслідок підвищення ризику нефротоксичності).
Cyclosporine. The injection of diclofenac on the activity of prostatglandins in nircah may suggest nephrotoxicity of cyclosporine. The doses of diclofenac that occur should be lower, lower in patients, if cyclosporine is not ingested.
Preparations for the treatment of hyperkalemia: Chronic ingestion of diclofenac with potassium-sparing diuretics, cyclosporine, tacrolimus, and trimethoprim can lead to an increase in plasma potassium levels (in times of such occurrence, the indicator is often to be controlled).
Antibacterial drugs are similar to quinolone. I was informed about the development of the court in ailments, as they immediately took away the effects of quinolone and diclofeac.
Transferring to and from each other
NPZZ and GKS. One-hour systemic ingestion of diclofenac and other systemic NSAIDs or corticosteroids may increase the incidence of non-negligible manifestations (zocrema, sideways SHT).
Anticoagulants and antiaggregants. It is necessary to carefully combine diclofenac with the drugs of the cich group due to the risk of bleeding. Irrespective of those who, in clinical trials, did not put diclofenac infusion for anticoagulant therapy, there is more information about the risk of bleeding in patients, if they took a combination of drugs. Therefore, in times of such a medical condition, it is recommended to be guarded for ailments.
Selective serotonin ingestion inhibitors. An overnight intake of diclofenac with selective serotonin ingestion inhibitors increases the risk of developing mucosal-intestinal bleeding.
Hypoglycemic drugs. In clinical studies, it was established that it is possible to inject diclofenac and hypoglycemic drugs overnight, with which the effectiveness of the remaining ones does not change. However, in addition to the information about the development of such disorders, both hypoglycemia and hyperglycemia, it suggested the need to change the dose of hypoglycemic drugs against the backdrop of diclofenac ingestion. Therefore, under the hour of sleeping diclofenac and hypoglycemic drugs, it is recommended to monitor the concentration of glucose in the blood.
Methotrexate. We should be careful if diclofenac is recognized less, lower 24 years before or 24 years after taking methotrexate, because in such cases, the concentration of methotrexate in the blood may increase and become toxic.
Phenytoip. In case of one-hour ingestion of fenntoin and diclofenac, it is necessary to control the concentration of phenytoin in the blood plasma through the possibility of increasing systemic infusion.
especially vkazіvki
Damage to SKT
In the case of diclofenac ingestion, such manifestations as bleeding or viral/perforated CT were noted, in a number of cases with a fatal outcome. These manifestations can be blamed for any hour in case of drug overdose in patients with the presence or absence of anterior symptoms and serious mucosal-intestinal ailments in history or without them. At years of patients similar aggravation can cause serious consequences. In case of development in patients, if you take Voltaren, bleeding or if you have SHT, the drug should be administered.
To reduce the risk of toxic effects on HCT in patients with severe HCT lesions, especially aggravated bleeding or perforation in history, as well as in patients with a frail age, the drug should be administered at the minimum effective dose.
Пацієнтам з підвищеним ризиком розвитку шлунково-кишкових ускладнень, а також пацієнтам, які отримують терапію низькими дозами ацетилсаліцилової кислоти (Аспірину), слід приймати гастропротектори (інгібітори протонної помпи або мізопростол) або інші медичні препарати для зниження ризику небажаного впливу на ШКТ. Patients with a history of lesions of the mucosal-intestinal tract, especially in summer, it is necessary to inform the doctor about all abdominal symptoms.
Patients with bronchial asthma
Acute bronchial asthma (NSAID intolerance/bronchial asthma provoked by NSAIDs), angioedema and kropivyanka are most commonly seen in patients who suffer from bronchial asthma, seasonal allergic rhinitis, and nasal polyps. ). In this group of patients, as well as in patients with allergies to other drugs (suspension, sverbіzh or kropivyanka) in case of congestion with the drug Voltaren slid dotrimuvatisya
special care (preparedness before resuscitation visits).
Shkirnі reactions
Such serious dermatological reactions, such as exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, in some cases with a fatal result, against the background of diclofenac ingestion, were rarely indicated. The greatest risk and frequency of development of severe dermatological reactions was observed in the first month of treatment with diclofenac. With the development of patients, if Voltaren is withdrawn, the first signs of skin visipu, mucosal lesions, or other symptoms of hypersensitivity, the drug is guilty of contact. In isolated cases in patients who are not allergic to diclofenac, anaphylactic / anaphylactoid reactions may develop when Voltaren is ingested.
Injection into the liver
Injection on nirks
На фоні терапії препаратом Вольтарен рекомендується проводити контроль функції нирок у пацієнтів з гіпертонічною хворобою, порушеннями функції серця або нирок, літніх пацієнтів, які отримують діуретики або інші препарати, що впливають на ниркову функцію, а також у пацієнтів зі значним зменшенням об'єму циркулюючої плазми be-like ethiology. , for example, in the period before that after massive surgical interventions. After the initiation of therapy with the drug, as a rule, normalization of the indicators in the nirkovoi function of the output values is expected.
Infusion into the cardiovascular system
NPSH therapy, incl. diclofenac, especially treatment with high doses of high doses, may be associated with a small increase in the risk of developing serious cardiovascular thrombotic conditions (including myocardial infarction in stroke).
У пацієнтів із захворюваннями серцево-судинної системи та високим ризиком розвитку захворювань серцево-судинної системи (наприклад, з артеріальною гіпертеїзією, гіперліпідемією, цукровим діабетом, курцям) слід застосовувати препарат з особливою обережністю, у найнижчій ефективній дозі при мінімально можливій тривалості лікування, оскільки ризик due to increased thrombotic complications due to increased doses and trivality. With triple therapy (more than 4 cycles), an additional dose of diclofenac in such patients may be increased to 100 mg. Next, periodically evaluate the effectiveness of the treatment and the patient's consumption in
symptomatic therapy, especially in depressions, if the symptoms become over 4 symptoms. If the first symptoms of thrombotic disorders appear (for example, pain in the breasts, if there are signs of insufficiency, weakness, damage to the movement), the patient should immediately seek medical help.
Injection into the hematopoietic system
Voltaren may temporally inhibit platelet aggregation. Therefore, in patients with impaired hemostasis, it is necessary to conduct a detailed control of the relevant laboratory indicators. In case of trivial stasis of Voltaren, it is recommended to conduct regular clinical analysis of peripheral blood.
Masking is a sign of an infectious process
The antiseptic drug Voltaren may complicate the diagnosis of infectious processes.
Zastosuvannya one hour with other NSAIDs
Do not stop taking Voltaren at the same time as the NSAID, including selective COX-2 inhibitors due to the risk of an increase in adverse events.
Having poured into the building a vicon of potentially unsafe types of activities, which require special respect and special reactions (management of transport barriers, robots with mechanisms that are collapsing thinly)
Patients who are on the background of drug exposure to Voltaren are blamed for severe damage, confusion, drowsiness, vertigo or other damage to the central nervous system are not followed by transport means and mechanisms.
Vagity and lactation
There is not enough data on the safety of diclofenac ingestion in female women. Prescribe the drug Voltaren in the 1st and 2nd trimesters of pregnancy, but less in depressions, if the measles for the mother outweighs the potential risk for the fetus. Voltaren, as an inhibitor of the synthesis of prostaglandins, contraindications in the remaining 3 months of pregnancy (possibly strangulation of the rapid uterine growth and pre-existing occlusion of the arterial duct in the fetus).
Regardless of those that the drug Voltaren, as well as other NPZZ, penetrates into breast milk in a small amount, the drug is not suitable for women who are aged, for the fear of the careless infusion on the child. If necessary, the drug Voltaren should be administered to a woman who is breast-feeding.
Oskilki Voltaren, as well as other NPZZ, can negatively affect fertility, women who plan to conceive, are not recommended to take the drug.
Patients who need to pass obstezhennya and likuvannya without a drive, the drug should be prescribed.
Zastosuvannya at the child's vіtsi
Contraindications for children under 18 years of age.
In case of damage to the function of the nirok
На тлі терапії препаратом Вольтарен рекомендується проводити контроль функції нирок у пацієнтів з гіпертонічною хворобою, порушеннями функції серця або нирок, літніх, пацієнтів, які отримують діуретики або інші препарати, що впливають на ниркову функцію, а також у пацієнтів із значним зменшенням обсягу циркулюючої плазми будь -what ethiology, for example, in the period before that after massive surgical interventions. After the initiation of therapy with the drug, as a rule, normalization of the indicators in the nirkovoi function of the output values is expected.
With impaired liver function
Oskilki in the period of suspension of the drug Voltaren may lead to an increase in the activity of one or more liver enzymes, with triple therapy with the drug, as an afterthought, indications of control of liver function. If the progression of hepatic function impairment is preserved, or it is a sign of liver disease or other symptoms (for example, eosinophilia, viscera lean), taking the drug should be administered. It has been observed that hepatitis in the background of drug exposure to Voltaren may develop without prodromal manifestations.
Zastosuvannya at the summer residence
Correction of the cob dose in patients at age 65 and no more needed. In debilitated patients, patients with low body weight, it is recommended to increase the minimum dose.
Wash your permits from pharmacies
For a prescription.
Wash that term saving
For temperatures not higher than 30°C. Zapobіgati infusion of light and high temperatures. The drug should be taken from a place inaccessible to children. The term of appurtenance - 2 years.
The drug does not follow vikoristovuvaty after the end of the term of applicability, stated on the package.
Voltaren is a non-steroidal antispasmodic drug that is used to relieve the pain syndrome of varicose veins.
Fluid speech - Diclofenac - can be anti-inflammatory, antipyretic and analgesic, as a result of which the synthesis of prostaglandins is reduced, as mediators of inflammation, pain and fever.
A decrease in the number of prostaglandins in the inflamed cavity causes an analgesic effect of the drug, and a decrease in prostaglandins in the hypothalamus is an antipyretic effect.
Voltaren in the treatment of primary dysmenorrhea does not only reduce pain, but significantly reduces blood loss.
After an intravenous injection of 75 mg of diclofenac sodium, it starts to get wet. The mean value of the maximum plasma concentration becomes close to 2.5 µg/ml (8 µmol/l) and is reached in about 20 minutes. With intravenous administration, the therapeutic concentration in the blood is within reach. The lineage of the amount of the active ingredient to be wetted, depending on the dosage of the Voltaren injection, should be checked.
Indication before zastosuvannya
Why do Voltaren injections help? According to the instructions, the drug is prescribed for such cases:
- ankylosing spondylitis;
- osteoarthritis;
- spondyloarthritis;
- bіl at the ridge;
- illness of zaglobovih soft tissue and rheumatic character;
- pain syndrome, as well as swelling and inflammation of the soft tissues and globules, which were caused by injuries;
- primary dysmenorrhea and other gynecological diseases that are accompanied by inflammation and/or pain.
Rozchin for vnutrishnyom'yazovih or vnutrishnyovennyh іn'єktsіy also mozhe zastosovuvatisya for any kind of pain sensations, as a result of the ignition process.
The drug may have an analgesic effect, it does not affect the progression of the disease.
Instructions for administering Voltaren injections, dosing
Rozchin for injections of appointments for internal and external administration. The injection is more often fought internally, after the recognition of the doctor. Internal administration is allowed due to the pronounced intensity of pain sensations.
It is not recommended to stop the injection more than 2 days later. Trivaliy course of treatment is not recommended, because in this case there is a risk of development of side effects. The maximum duration of the drug intake is 5 days.
At times of consumption, it is possible to combine injections of Voltaren with other dosage forms of the drug, but it is not recommended to increase the additional dose of 150 mg.
The drug is injected deeply into the m'yaz, the upper ovn_shn_y sidnichny square. The standard dosage of Voltaren according to the instructions is 75 mg (1 ampoule) 1 time per day.
For migraine attacks, 75 mg (1 ampoule) is prescribed. The best effect is achieved, like an injection of Voltaren to stun the yakomog earlier after the cob attack. It is necessary, every day, to take suppositories in doses up to 100 mg. The total additional dose is not guilty of becoming more than 175 mg.
In times of severe pain syndrome, 2 injections with an interval of a few years may be indicated, in such a case, another injection should be given to the opposite side.
Side effects
Instructions ahead about the possibility of development of offensive side effects in case of recognized injections of Voltaren:
- Herbal system - nausea, vomit, pain in the abdomen, bloating (flatulence), decreased appetite right up to anorexia (stomatitis (inflammation of the mucous membrane of the empty mouth), membrane stricture of the intestine. Sometimes pancreatitis can develop (inflammation of the scrotum). In lonely cases, there may be a development of gastritis (inflamed mucous membrane of the sac) and slunic-intestinal bleeding.
- Liver and liver paths - increase in the blood level of hepatic enzymes (AST, ALT), which indicates the deterioration of hepatocytes, drug-induced toxic hepatitis, impaired liver function with the development of cholestatic liver disease.
- Nervous system - depression (expression and depression of the mood), disorientation in the hour of that space, disturbed sleep, head pain, noise in the ears, aseptic meningitis (non-infectious inflammation of the meninges), slutaniye of the bridge, hallucinations, dyslexia. More likely development by the court
- Eyes - blurred vision, diplopia (double vision), neuritis of the optic nerve.
- Cardio-vascular system - palpitations, tachycardia (often heart failure), development of heart failure, vasculitis (inflamed vessels), decreased level of systemic arterial pressure (arterial hypotension).
- Organic respiratory disorders - asthma (bronchospasm with ringing and impaired air passage), pneumonitis (inflammation of the alveoli of the lungs).
- Shkіra and pіdshkіrna kіtkovina - Stevens-Johnson syndrome (appearance of multiple bulbs on the skin, covered with mother tongue), toxic epidermal necrolysis, erythema (reddened skin), alopecia (hair loss).
- Sechostateva system - hospital deficiency, interstitial nephritis (inflamed nirok), papillary necrosis (death of clitin papillae in nirok), people can rarely develop impotence.
- The blood system and the red cystic brain - thrombocytopenia (decrease in the number of platelets in the blood), leukopenia (change in leukocytes) and anemia (anemia).
- Allergic reactions - often develop visip on the shkіrі, її sverbіzh i kropiv'yanka (characteristic visip and swelling of the shkіri, which predict opik ropiva). RIDSHAVIVEVEVEN VAKA ALERGICHNA of reaction at Vighidi Angiourotical Naborika (vihiyaks of Shkіri that pіdshkirno klitkovini in the Opokoye Subtevich Organizov) abed anathylactic shock.
- Reactions in the area of the injection in the presence of infiltrate (strengthening of the skin or sub-shkirnoy cellular tissue), blackening of the skin. In times of infection, the injection site may have a development of a subcutaneous abscess (formation of an obstructed stool filled with pus).
Contraindication
Voltaren injections are contraindicated in such cases:
- Virazkov's ailment of the intestine and the twelve-fingered intestine in the acute phase (internal bleeding, perforation);
- Crohn's ailment, virazkovy colitis and other destructive-inflammatory inflammation of the intestines in the acute phase;
- Severe form of nirk, liver, heart failure;
- Active disease of the liver;
- Coronary artery bypass grafting;
- Hyperkalemia (diagnosed);
- period of vaginess;
- Childhood and child age up to 18 years;
- Become, scho suprovodzhuyutsya risky development of bleeding.
З обережністю призначати пацієнтам з бронхіальною астмою, серцево-судинними захворюваннями або високим ризиком їх розвитку, сезонним алергічним ринітом, хронічними інфекційними патологіями дихальної системи, набряком слизової оболонки носа (у тому числі при поліпах), цукровим діабетом, артеріальною гіпертензією. damage to the system of hemostasis, alcohol and / or tyutyunovoy zalezhnistyu.
With special care to zastosovuyut at the liking of patients of a frail age.
Overdose
Symptoms of overdose - noise in the mouth, zamorochennya, ship attacks, slug-intestinal bleeding, vomit. When congested at even high doses, it is possible to severely damage the liver and develop acute insufficiency.
Carry out general detoxification and symptomatic therapy.
Analogues Voltaren, price in pharmacies
If it is necessary to replace the injection of Voltaren, it is possible for an analogue according to the active speech - the whole preparation:
- Dicloberl,
- Diklak,
- Dicloran.
Choosing analogues, it is important to understand that the instructions from Voltaren's quotation, the price and recommendations for preparations similar to those do not expand. It is important to take the advice of the doctor and do not carry out self-replacement of the drug.
Price in Russian pharmacies: Voltaren ampoules 75 mg 3 ml 5 pieces - from 243 to 298 rubles, for 509 pharmacies.
The term of applicability for injection into Voltaren becomes 2 years from the moment of preparation. The drug should be taken in a dark, dry area, inaccessible to children, at a temperature not higher than +30°C.
What do they say?
People, who have taken the drug, are deprived of positive feedback about Voltaren injections - it is expected to report strong anti-inflammatory and analgesic effects on the drug, as well as a rare vindication of negative side effects in the analogous drug use.
especially vkazіvki
Before the start of the course of treatment and zastosuvannyam razchiny for the injection of Voltaren, it is necessary to carry out a test for sensitivity and manifestation of allergy, which is better for the first introduced minimal dose.
Under the hour of treatment with the drug, it is necessary to control the state of the herbal system, in case of primary symptoms, which indicate possible bleeding, stop the cause for injections of the next injection.
In times of concomitant pathology of the intestinal tract, there is a need for the necessary parallel injection of drugs that reduce the acidity of the intestinal juice and envelop the mucous membrane.
According to the schedule for injections of Voltaren, periodic laboratory monitoring of indications of the functional activity of the liver and blood system was carried out.
In I and II trimesters of pregnancy, the recognition of the drug may be less in case of depression, as a result of the measles for the mother outweighing the potential risk for the fetus. The appointment of Voltaren injections in the III trimester of pregnancy and the first hour of breastfeeding is not recommended.
Medical interaction
One-hour administration of the drug with CYP2C9 inhibitors increases the concentration of diclofenac in the blood.
Voltaren may be given instead of digoxin and lithium in plasma.
The drug reduces the effect of hypotensive and diuretic effects.
The use of diclofenac with anticoagulants, antiplatelet agents, and serotonin ingestion inhibitors increases the risk of bleeding in patients.
Overnight exposure to other non-steroidal anti-inflammatory drugs (NPZP) increases the risk of developing side effects.
Sleeping with hypoglycemia is allowed with regular monitoring of the concentration of glucose in the blood.
One-hour use with potassium-sparing diuretics may cause an increase in potassium levels in the blood.
Voltaren improves the nephrotoxicity of cyclosporine and systemic phenytoin.